Submitted by san2025 on January 12, 2022 - 9:50pm
| Title | Clinical failure of vancomycin in a dialysis patient with methicillin-susceptible vancomycin-heteroresistant S. aureus. |
| Publication Type | Journal Article |
| Year of Publication | 2009 |
| Authors | Fusco DN, Alexander EL, Weisenberg SA, Mediavilla JR, Kreiswirth BN, Schuetz AN, Jenkins SG, Rhee KY |
| Journal | Diagn Microbiol Infect Dis |
| Volume | 65 |
| Issue | 2 |
| Pagination | 180-3 |
| Date Published | 2009 Oct |
| ISSN | 1879-0070 |
| Keywords | Animals, Anti-Bacterial Agents, Bacteremia, Female, Humans, Methicillin, Middle Aged, Renal Dialysis, Staphylococcal Infections, Staphylococcus aureus, Treatment Failure, Vancomycin, Vancomycin Resistance |
| Abstract | We report a case of recurrent Staphylococcus aureus bacteremia in a patient who failed vancomycin due to a vancomycin-heteroresistant strain lacking methicillin resistance. Although initial isolates were susceptible, isolates obtained after vancomycin chemotherapy were vancomycin heteroresistant. This case thus illustrates the clinical emergence of vancomycin heteroresistance. |
| DOI | 10.1016/j.diagmicrobio.2009.05.017 |
| Alternate Journal | Diagn Microbiol Infect Dis |
| PubMed ID | 19748429 |
| PubMed Central ID | PMC5227555 |
| Grant List | T32 AI007613 / AI / NIAID NIH HHS / United States AI 007613 / AI / NIAID NIH HHS / United States |