Publications

Wang Z, Soni V, Marriner G, Kaneko T, Boshoff HIM, Barry CE, Rhee KY.  2019.  Mode-of-action profiling reveals glutamine synthetase as a collateral metabolic vulnerability of M. tuberculosis to bedaquiline.. Proc Natl Acad Sci U S A. 116(39):19646-19651.

Lu X, Williams Z, Hards K, Tang J, Cheung C-Y, Aung HLin, Wang B, Liu Z, Hu X, Lenaerts A et al..  2019.  Pyrazolo[1,5- a]pyridine Inhibitor of the Respiratory Cytochrome bcc Complex for the Treatment of Drug-Resistant Tuberculosis.. ACS Infect Dis. 5(2):239-249.

Carette X, Platig J, Young DC, Helmel M, Young AT, Wang Z, Potluri L-P, Moody CStuver, Zeng J, Prisic S et al..  2018.  Multisystem Analysis of Mycobacterium tuberculosis Reveals Kinase-Dependent Remodeling of the Pathogen-Environment Interface.. mBio. 9(2)

Kumar P, Capodagli GC, Awasthi D, Shrestha R, Maharaja K, Sukheja P, Li S-G, Inoyama D, Zimmerman M, Liang HPin Ho et al..  2018.  Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA.. mBio. 9(6)

Irnov I, Wang Z, Jannetty ND, Bustamante JA, Rhee KY, Jacobs-Wagner C.  2017.  Crosstalk between the tricarboxylic acid cycle and peptidoglycan synthesis in Caulobacter crescentus through the homeostatic control of α-ketoglutarate.. PLoS Genet. 13(8):e1006978.

Park Y, Pacitto A, Bayliss T, Cleghorn LAT, Wang Z, Hartman T, Arora K, Ioerger TR, Sacchettini J, Rizzi M et al..  2017.  Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis.. ACS Infect Dis. 3(1):18-33.

Puckett S, Trujillo C, Wang Z, Eoh H, Ioerger TR, Krieger I, Sacchettini J, Schnappinger D, Rhee KY, Ehrt, Sabine.  2017.  Glyoxylate detoxification is an essential function of malate synthase required for carbon assimilation in Mycobacterium tuberculosis.. Proc Natl Acad Sci U S A. 114(11):E2225-E2232.

Eoh H, Wang Z, Layre E, Rath P, Morris R, D Moody B, Rhee KY.  2017.  Metabolic anticipation in Mycobacterium tuberculosis.. Nat Microbiol. 2:17084.

Hartman TE, Wang Z, Jansen RS, Gardete S, Rhee KY.  2017.  Metabolic Perspectives on Persistence.. Microbiol Spectr. 5(1)

Boyle KE, Monaco HT, Deforet M, Yan J, Wang Z, Rhee K, Xavier JB.  2017.  Metabolism and the Evolution of Social Behavior.. Mol Biol Evol. 34(9):2367-2379.

Samuels DJ, Wang Z, Rhee KY, Brinsmade SR.  2017.  A Tandem Liquid Chromatography-Mass Spectrometry-based Approach for Metabolite Analysis of Staphylococcus aureus.. J Vis Exp. (121)