Publications

Liang RJ, Taylor S, Nahiyaan N, Song J, Murphy CJ, Dantas E, Cheng S, Hsu T-W, Ramsamooj S, Grover R et al..  2021.  GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase.. Cancer Metab. 9(1):12.

Li S-G, Vilchèze C, Chakraborty S, Wang X, Kim H, Anisetti M, Ekins S, Rhee KY, Jacobs WR, Freundlich JS.  2015.  Evolution of a thienopyrimidine antitubercular relying on medicinal chemistry and metabolomics insights.. Tetrahedron Lett. 56(23):3246-3250.

Lemos MP, McKinney J, Rhee KY.  2011.  Dispensability of surfactant proteins A and D in immune control of Mycobacterium tuberculosis infection following aerosol challenge of mice.. Infect Immun. 79(3):1077-85.

Lemos MP, Rhee KY, McKinney JD.  2011.  Expression of the leptin receptor outside of bone marrow-derived cells regulates tuberculosis control and lung macrophage MHC expression.. J Immunol. 187(7):3776-84.

Lazar N, Fay A, Nandakumar M, Boyle KE, Xavier J, Rhee K, Glickman MS.  2017.  Control of biotin biosynthesis in mycobacteria by a pyruvate carboxylase dependent metabolic signal.. Mol Microbiol. 106(6):1018-1031.

Lakshmanan V, Rhee KY, Daily JP.  2011.  Metabolomics and malaria biology.. Mol Biochem Parasitol. 175(2):104-11.

Lakshmanan V, Rhee KY, Wang W, Yu Y, Khafizov K, Fiser A, Wu P, Ndir O, Mboup S, Ndiaye D et al..  2012.  Metabolomic analysis of patient plasma yields evidence of plant-like α-linolenic acid metabolism in Plasmodium falciparum.. J Infect Dis. 206(2):238-48.

Kumar P, Capodagli GC, Awasthi D, Shrestha R, Maharaja K, Sukheja P, Li S-G, Inoyama D, Zimmerman M, Liang HPin Ho et al..  2018.  Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA.. mBio. 9(6)

Krisko TI, Nicholls HT, Bare CJ, Holman CD, Putzel GG, Jansen RS, Sun N, Rhee KY, Banks AS, Cohen DE.  2020.  Dissociation of Adaptive Thermogenesis from Glucose Homeostasis in Microbiome-Deficient Mice.. Cell Metab. 31(3):592-604.e9.

Kardon JR, Yien YY, Huston NC, Branco DS, Hildick-Smith GJ, Rhee KY, Paw BH, Baker TA.  2015.  Mitochondrial ClpX Activates a Key Enzyme for Heme Biosynthesis and Erythropoiesis.. Cell. 161(4):858-67.

Jansen RS, Rhee KY.  2017.  Emerging Approaches to Tuberculosis Drug Development: At Home in the Metabolome.. Trends Pharmacol Sci. 38(4):393-405.

Jansen RS, Mandyoli L, Hughes R, Wakabayashi S, Pinkham JT, Selbach B, Guinn KM, Rubin EJ, Sacchettini, James C, Rhee KY.  2020.  Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis.. Nat Commun. 11(1):1960.

Isa F, Collins S, Lee MHee, Decome D, Dorvil N, Joseph P, Smith L, Salerno S, Wells MT, Fischer S et al..  2018.  Mass Spectrometric Identification of Urinary Biomarkers of Pulmonary Tuberculosis.. EBioMedicine. 31:157-165.

Irnov I, Wang Z, Jannetty ND, Bustamante JA, Rhee KY, Jacobs-Wagner C.  2017.  Crosstalk between the tricarboxylic acid cycle and peptidoglycan synthesis in Caulobacter crescentus through the homeostatic control of α-ketoglutarate.. PLoS Genet. 13(8):e1006978.

Hodakoski C, Hopkins BD, Zhang G, Su T, Cheng Z, Morris R, Rhee KY, Goncalves MD, Cantley LC.  2019.  Rac-Mediated Macropinocytosis of Extracellular Protein Promotes Glucose Independence in Non-Small Cell Lung Cancer.. Cancers (Basel). 11(1)

Hartman TE, Rhee KY.  2015.  Microbial Metabolomics: Fifty Shades of Metabolism.. ACS Infect Dis. 1(1):73-5.

Hartman TE, Wang Z, Jansen RS, Gardete S, Rhee KY.  2017.  Metabolic Perspectives on Persistence.. Microbiol Spectr. 5(1)

Hards K, Adolph C, Harold LK, McNeil MB, Cheung C-Y, Jinich A, Rhee KY, Cook GM.  2020.  Two for the price of one: Attacking the energetic-metabolic hub of mycobacteria to produce new chemotherapeutic agents.. Prog Biophys Mol Biol. 152:35-44.

Gouzy A, Healy C, Black KA, Rhee KY, Ehrt, Sabine.  2021.  Growth of Mycobacterium tuberculosis at acidic pH depends on lipid assimilation and is accompanied by reduced GAPDH activity.. Proc Natl Acad Sci U S A. 118(32)

Goncalves MD, Lu C, Tutnauer J, Hartman TE, Hwang S-K, Murphy CJ, Pauli C, Morris R, Taylor S, Bosch K et al..  2019.  High-fructose corn syrup enhances intestinal tumor growth in mice.. Science. 363(6433):1345-1349.

Ginn J, Jiang X, Sun S, Michino M, Huggins DJ, Mbambo Z, Jansen R, Rhee KY, Arango N, Lima CD et al..  2021.  Whole Cell Active Inhibitors of Mycobacterial Lipoamide Dehydrogenase Afford Selectivity over the Human Enzyme through Tight Binding Interactions.. ACS Infect Dis. 7(2):435-444.

Gardiner DF, Rhee KY.  2006.  An unusual cause of ST segment elevation. Brugada syndrome.. Clin Infect Dis. 42(6):826-7,885-6.

Ganapathy U, Marrero J, Calhoun S, Eoh H, de Carvalho LPedro Sori, Rhee K, Ehrt, Sabine.  2015.  Two enzymes with redundant fructose bisphosphatase activity sustain gluconeogenesis and virulence in Mycobacterium tuberculosis.. Nat Commun. 6:7912.

Fusco DN, Alexander EL, Weisenberg SA, Mediavilla JR, Kreiswirth BN, Schuetz AN, Jenkins SG, Rhee KY.  2009.  Clinical failure of vancomycin in a dialysis patient with methicillin-susceptible vancomycin-heteroresistant S. aureus.. Diagn Microbiol Infect Dis. 65(2):180-3.

Eoh H, Rhee KY.  2013.  Multifunctional essentiality of succinate metabolism in adaptation to hypoxia in Mycobacterium tuberculosis.. Proc Natl Acad Sci U S A. 110(16):6554-9.